The correct form of "to be" to fill in the gap is "is".
So, the completed sentence is:
A lion is a big cat.
**Explanation:**
In English, the verb "to be" has different forms depending on the subject. For singular subjects (like "a lion"), we use "is" in the present tense. Other forms include:
* **am**: used with the subject "I" (e.g., "I am a student").
* **are**: used with plural subjects (e.g., "They are friends") or the subject "you" (e.g., "You are kind").